Medicinal Chemist – Principal Scientist - santiago de compostela - Celtarys

Descripción

• A PhD in Medicinal Chemistry with > 2 years' experience as Post doc.
• Extensive and accreditated experience in (in order of relevance):
  • Knowledge of medicinal chemistry basis and approaches to modify molecules structures to improve their bioactivity;
  • Understanding of molecule/target interaction principles and modes;
  • Deep understanding of the biological data related to the compounds developed to incorporate them into new designs and/or potential refinement of molecular probes leading to successful experimental outcomes;
  • Independent design of new molecules able to interact with specific targets of interest;
  • Organic synthesis: full autonomy in design and realization of multipstep synthesis (also more than 6-7 steps) for the obtention of complex molecular structure with specific restrictions in terms of stability (such as fluorophores, biomolecules derivatives, etc.);
  • Strong and wide knowledge of biomolecules and small molecules purification and characterization approaches;
  • Strong independence, problem solving, troubleshooting skills and proven ability to lead research projects;
  • Responsible and goal-oriented professional, able to integrate into a multidiciscplinary team and work in a competitive environment, dealing with multiple projects and client deadlines.
  • Fluent in English

• Lead and coordinate the conceptualization, design and execution of research projects for the development fluorescent probes and other bioactive polyfunctional compounds.
• Manage projects assigned and clients scientific requests;
• Learn and apply state-of-the-art enabling technologies, specifically related to molecular design and organic synthesis (e.g. NMR, HPLC, mass spectrometry, etc.)
• Disciplined decision making, strategic thinking, and creative problem solving;
• Collaborate with chemistry and biology department collegues locally and throughout our collaborating research groups, companies and entities.
• Present ideas and results internally to discuss about possible issues/solutions and alternatives.

• The opportunity to open and lead new research lines within a growing innovative company
• Working within a young and committed team, with a sound scientific base and a unique patented technology
• Fixed competitive salary according to the experience and capabilities of the candidate
• Full time position and flexible working environment