Vac_02_2025 - Bioinformatics Technician - Barcelona - Institut De Recerca Contra La Leucèmia Josep...

Descripción

The Josep Carreras Leukaemia Research Institute is a comprehensive cancer research center dedicated to conducting research and driving innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies with the final aim of finding a cure for these diseases.

Research Description

Hematopoietic stem cells are a life-saving therapy for leukemia and have broadened applications to gene and cell therapy against other cancers genetic autoimmune and infectious diseases yet practical limitations such as donor-matching or insufficient cell number render these therapies unfeasible or unsuccessful for many patients attempts to overcome these limitations have been unable to create a reliable source of HSC for patients while we can generate human HSC from pluripotent stem cells they resemble early development stages lacking many of the functional maturation hallmarks.

Main Responsibilities

• Analysis and integration of bulk and single-cell NGS data e.g RNA-seq ATACseq spatial transcriptomics of human hematopoietic stem cells and tissues
• Coordination with team members and collaborators for optimal extraction of the biological information
• Curation of data and code repositories

Requirements

We are looking for a BIOINFORMATICS TECHNICIAN to join the Blood Stem Cell Identity group led by Dr Vincenzo Calvanese to work on a Project to identify transcriptional regulation mechanisms that sustains HSC self-renewal and their relevance for the establishment and maintenance of the leukemia stem cell population in the context of blood cancer.

What We Need

• A Master of Science in Bioinformatics Computational biology and/or a related degree
• C R Python bash programming experience
• Proven expertise of single-cell dataset analysis and/or genomics/transcriptomics analysis
• Proficiency in Unix/Linux environments
• Experience with software version control or HPC environments SLURM
• Fundamental knowledge of cellular and molecular biology
• Experience in Stem cell biology and/or hematopoiesis will be valued

What We Offer

• A full-time technician contract linked to Project PID2023-152341OB-I00 funded by MICIU/AEI /10.13039/501100011033 and by FEDER EU
• The opportunity to contribute to a cutting-edge research project in the stimulating environment of the Josep Carreras Leukaemia Research Institute
• The vibrant scientific and cultural environment of the Barcelona metropolitan area

About Us

The mission of the Josep Carreras Institute is to conduct research and drive innovation in the epidemiological preventive clinical translational and basic aspects of leukaemia and other hematologic malignancies with the final aim of finding a cure for these diseases.

The IJC's vision is to be a world-class reference and excellent research multicampus that contributes to the improvement of results and the cure of patients affected by leukemia and other malignant hemopathies through innovation sustainability social responsibility talent and professional experience.