Master's/phd Thesis Position: Cmos Design of - Barcelona, España - Consejo superior de investigaciones cientificas

Consejo superior de investigaciones cientificas
Consejo superior de investigaciones cientificas
Empresa verificada
Barcelona, España

hace 1 mes

Isabel García

Publicado por:

Isabel García

beBee Recruiter
Descripción
"Organ-on-chip" (OoC) technology - understood as the microfabrication of cell culture devices to model functional units of human organs in vitro - has seen significant advancements in recent years. OoC is transforming biomedical research by replicating organ-level physiology within complex and controlled microenvironments. However, its progress is hindered by current knowledge gaps in the spatiotemporal dynamics involved in the development of organoids, which are three-dimensional cell tissue cultures with enormous potential to revolutionize the control over specific physiological and pathological responses of human organs in OoC.


In this project, you will collaborate with a multidisciplinary team with expertise in neuroscience, microelectronics, chemistry, and computational biology, incorporating the latest advances in CMOS biochemical sensors and neuromorphic engineering to develop the first smart biochip for precise interpretation of organoid biochemical activity in organ-on-chip platforms.

You will investigate new ultra-low-power ICs for the readout of micron-sized sensor arrays for non-optical electrochemical imaging, which can be integrated to provide comprehensive chemical analyses in the miniaturized dimensions of organoids-on-chip.

The readout circuits will be optimized to (i) deliver tunable compression of interfering components to enhance measuring resolution, and (ii) distributed event-based encoding to boost performance in posterior neuro-AI processing stages.

**Your tasks: - Design of neuromorphic readout architectures for multimodal sensing. This includes developing sensor analog frontends, asynchronous A/D converters, and the digital communication stages. You will integrate your circuit proposals in sub-micron CMOS technologies;

  • Tapeout of your own custom chips and electrochemical characterization; Integration into a labonachip device and validation through biochemical assays carried on real organoids.
**Your profile: - Finishing a Master's degree in Electronics/IT Engineering (or similar) covering analog/mixed-signal VLSI design;

  • Competence with Cadence EDA tools for CMOS circuit design;
  • Experience with PCB design and FPGA/embedded systems programming;
  • Researchoriented attitude, capable of taking initiatives and with a solid problemsolving attitude;
  • Ability to work in an interdisciplinary team; Fluent in spoken and written English.
**What we offer: - Full-time employment for 3 years (extendable), with an official go/no-go assessment within 6 months;

  • An excellent technical infrastructure in a stimulating, multidisciplinary, and dynamic environment;
  • Extensive benefits package for worklife balance in line with Spanish Administration's and CSIC's regulations;
  • International collaboration network with possibility to perform research stays among partners in related European and National projects;
  • Personalized handson training on cuttingedge technology topics with links to industry; Opportunity to join an ongoing startup project as entrepreneur.
**Application procedure: - A brief description of your main motivation for joining our team;

  • Your CV, highlighting relevant experience and accomplishments in related areas;
  • Contact details of at least 2 references; A transcript of your academic records including undergraduate and master's studies.