Postdoctoral Researcher - Barcelona, España - Center for Genomic Regulation

Isabel García

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Isabel García

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Descripción

The Institute


The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries.

The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.


In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' Award from the European Commission.

This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).

Please, check out our Recruitment Policy


The role


We are seeking a highly motivated
Postdoctoral Researcher, ideally with mixed/hybrid background in
Molecular Biology (wet lab) & Bioinformatics (dry lab), to join the Epitranscriptomics and RNA Dynamics group (PI: Eva Novoa), to the study of the role of RNA modifications (the "epitranscriptome") in neuronal activation and differentiation using nanopore sequencing technologies.


About the lab


Our lab is focused on deciphering the role that RNA modifications play in a large variety of cellular contexts, including the development of novel technologies to map RNA modifications.

In our lab, we are employing a combination of experimental (RNASeq, RIP-Seq polysome profiling, mouse/cell knockouts, Oxford Nanopore direct RNA sequencing) and computational techniques (NGS data analysis, algorithm development, machine learning), to unveil the secrets of three post-transcriptional regulatory layers: the epitranscriptome, RNA structure and ribosome specialization.


Whom would we like to hire?

Professional experience
You have to also possess the following key skills and attributes:

Must Have

  • A PhD in Molecular Biology, Biomedicine or similar
  • Background in RNA biology
  • Experience with mammalian cell cultures
  • You have published at least one primary research paper during your PhD

Desirable but not required/ Nice to have

Wet lab:

  • Experience in neuronal differentiation and/or activation
  • Experience with RNA-FISH and/or subcellular RNA localization techniques (e.g. SunTag)
  • Experience with Oxford Nanopore sequencing library preparation

Dry lab:

  • Ability to code in R and/or Python
  • Ability to use HPC clústers to submit jobs
  • Experience in the analysis of nanopore sequencing data
  • Experience in the analysis of illumina sequencing data

Education and training

  • You hold a PhD degree in Molecular Biology, Biology, Biochemistry or similar field

Languages

  • You must be fluent in oral and written
    English

Competences

  • You have excellent analytical and problemsolving skills
  • You have the capacity for carrying out duties under mínimal supervision
  • You have the drive and commitment to produce high quality experimental outcomes
  • You have highly developed organization skills
  • You have the ability to work as part of a team
  • You have good academic writing skills

The Offer - Working Conditions
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Contract duration:3 years

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Estimated annual gross salary:Salary is commensurate with qualifications and consistent with our pay scales
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Target start date:1st September 2023

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.


We offer and
promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.


The
CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.


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