Phd Position - Barcelona, España - Vall d'Hebron Institut de Recerca

Vall d'Hebron Institut de Recerca

Empresa verificada

Barcelona, España

hace 2 semanas

Publicado por:

Isabel García

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Descripción

TheVall d'Hebron Research Institute
(VHIR) is a public sector institution that
promotes and develops the research,
innovation and biosanitary teaching of the
Vall d'Hebron University Hospital. Through
the excellence of our research, we identify
problems of society and we contribute to
spread them around the world.

In April 2015, the
Vall d'Hebron

Research Institute (VHIR) obtained
the recognition of the European
Commission
HR Excellence.
This recognition proves that VHIR
endorses the general principles of the
European Charter for Researchers and
a Code of Conduct for the Recruitment
of Researchers
(Charter & Code).

VHIR embraces Equality and

Diversity. As reflected in our values

we work toward ensuring inclusion

and equal opportunity in

recruitment, hiring, training, and

management for all staff within the

organization, regardless of gender,

civil status, family status, sexual

orientation, religion, age, disability

or race.

PhD Position

MSCA-COFUND- TOUCH programme (Psychiatry, Mental Health and Addictions

Research Group)

TOUCH ("Towards the next generatiOn of excellent yoUng doctoral researchers on mental health by developing an
intersectoral & transdisciplinary approaCH") is a new excellent
doctoral programme led by the Universitat Autònoma de
providing a new dimension through highly interdisciplinary and intersectoral research while fulfilling all the principles of
Open Science and maintaining the highest research quality standards. UAB is the main Beneficiary and coordinator of
the programme
(12 doctoral positions offered) together with 7 institutions from the Sphere UAB-CIE as Implementing
partners by recruiting, hosting, and training PhD students.

Research Project description:

PhD will investigate mechanisms underlying the intergenerational transmission of risk for psychopathology and mental
disorders (parental genotypes).

There is evidence supporting that psychopathology is transmitted across generations. Children with parents with high
rates of psychopathology are more likely to inherit both psychopathology-associated genetic factors and
psychopathology-associated environments. However, it remains challenging to determine whether children resemble their
parents due to the effects of genes shared between them (direct genetic transmission or genetic nature), via genetically
influenced parenting environments (genetic nurture) or a mixture of both.

Parents transmit genetic risk for psychopathology and mental disorders to their children not only directly (genetic nature),
but also indirectly via genetically influenced parents' phenotype (genetic nurture).

To assess the mechanisms underlying the intergenerational transmission of parent psychopathology to offspring mental
health outcomes by exploring the distinction between transmitted and non-transmitted genetic factors from parents to
offspring. We will calculate polygenic risk scores (PRS), which aggregate the effects of thousands of genetic variants and
provides a quantitative measure of the genetic burden for a particular disease or trait, separately for transmitted and non
- transmitted genetic variants for multiple mental disorders (attention-deficit and hyperactivity disorder (ADHD), autism

TheVall d'Hebron Research Institute
(VHIR) is a public sector institution that
promotes and develops the research,
innovation and biosanitary teaching of the
Vall d'Hebron University Hospital. Through
the excellence of our research, we identify
problems of society and we contribute to
spread them around the world.

In April 2015, the
Vall d'Hebron

Research Institute (VHIR) obtained
the recognition of the European
Commission
HR Excellence.
This recognition proves that VHIR
endorses the general principles of the
European Charter for Researchers and
a Code of Conduct for the Recruitment
of Researchers
(Charter & Code).

VHIR embraces Equality and

Diversity. As reflected in our values

we work toward ensuring inclusion

and equal opportunity in

recruitment, hiring, training, and

management for all staff within the

organization, regardless of gender,

civil status, family status, sexual

orientation, religion, age, disability

or race.
spectrum disorder, bipolar disorder, depression, schizophrenia and anxiety, among others) in 1,500 general population
family trios and will test their association with behavioural and emotional problems and mental disorders in the offspring.

The impact of the proposal will be substantial in the fields of prevention and intervention. By identifying mechanisms
underlying the intergenerational transmission of risk for psychopathology and mental disorders we will provide insights
into the role of parents in shaping their children's outcomes and may identify modifiable parental factors that are likely to
be effective targets for intervention

Please consult the guidelines for app